Pregnant kidney transplant recipients with COVID-19; a report of two cases and literature review

Ana Domingos; António Braga; Daniela Gonçalves; Sofia Pedroso; La Salete Martins; Jorge Braga

doi:10.34172/jnp.2022.17291

doi: 10.34172/jnp.2022.17291

Abstract View: 1234

Case Report

Pregnant kidney transplant recipients with COVID-19; a report of two cases and literature review

Ana Domingos ¹^* , António Braga ² , Daniela Gonçalves ², Sofia Pedroso ³, La Salete Martins ³, Jorge Braga ²

¹ Department of Nephrology, Centro Hospitalar e Universitário do Algarve, Faro, Portugal
² Maternal-Fetal Unit, Obstetrics Department, Centro Materno Infantil do Norte, Centro Hospitalar e Universitário do Porto, Porto, Portugal
³ Department of Nephrology and Kidney Transplantation, Centro Hospitalar e Universitário do Porto, Porto, Portugal

*Corresponding author: Ana Domingos, Email: atdomingos@chalgarve.min-saude.pt

Abstract

If managing COVID-19 alone was a major challenge, one can expect an even greater challenge in certain scenarios, such as patients with kidney disease - including kidney transplant recipients (KT) – or pregnant women. When things could not get any worse, we just met the peculiar art of overcomplicating things: pregnant kidney and simultaneous kidney-pancreas (SKP) transplant recipients with COVID-19. Gleeson and colleagues (Imperial College, London) described the first similar case in April 2020. We describe two cases of pregnant KT and SKP transplant recipients with COVID-19, at different stages, and their evolution until delivery. Maternal and fetal outcomes are significantly affected by both KT and COVID-19, requiring a multidisciplinary approach with a well-trained team of obstetricians and nephrologists, as we will describe.

Keywords: Coronavirus, Pregnancy, Kidney transplant

Implication for health policy/practice/research/medical education:

In this case report, we describe two cases of kidney/pancreas transplant recipients who acquired COVID-19 during pregnancy.

Please cite this paper as: Domingos A, Braga A, Gonçalves D, Pedroso S, Martins LS, Braga J. Pregnant kidney transplant recipients with COVID-19; a report of two cases and literature review. J Nephropathol. 2022;11(x):exx. DOI: 10.34172/jnp.2022.xx.

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